JonnyBakes
02-28-05, 02:38 PM
After looking at these Boards for awhile and thinking about my TC problems and problems that plague many of us, I am wondering if there is any information or studies going on regarding chemoprevention in TC. By this I mean putting someone on a therapeutic meant to prevent progression of the disease (or eliminate occult disease). I know that researchers in many cancer fields are looking at various compounds to prevent relapse or recurrence and there are on going clinical trials in these areas.
The problem in my mind is that while I/O surgery cures a large percentage of TCs there is a large number who still develop disease. RPLND and chemo can cure many of those who still have disease which is awesome, but these treatments are fairly intense - maybe one-day there will be a better way.
In other cancers, such as colorectal cancer and prostate cancer, some compounds may have a "chemopreventative effect". There is also evidence that some natural products have chemopreventative effects, in some cancer models. Does anybody here know anything about this? I'd be interested in hearing more.
Also, does anybody have any info on TC pharmacogenomics?
The problem in my mind is that while I/O surgery cures a large percentage of TCs there is a large number who still develop disease. RPLND and chemo can cure many of those who still have disease which is awesome, but these treatments are fairly intense - maybe one-day there will be a better way.
In other cancers, such as colorectal cancer and prostate cancer, some compounds may have a "chemopreventative effect". There is also evidence that some natural products have chemopreventative effects, in some cancer models. Does anybody here know anything about this? I'd be interested in hearing more.
Also, does anybody have any info on TC pharmacogenomics?