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LDH high 2 cycles in

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  • LDH high 2 cycles in

    My tumor markers were never high pre chemo, now starting bep 3/3 we ran setums again. Afp and HCG both look good but my LDH is at 487.

    I know LDH is pretty non-specific and my oncologist isn't worried about it much, but I just wanted to run that number by people here to see if they agree.

    I've been getting nuelasta if that matterd
    *** Serum Markers Never High*** July 14, 2017: Lump on right testicle July 18: Urologist orders U/S July 20: US show 3 lesions "highly suspicious for testicular cancer" July 26: Pelvic CT shows 1 lymph node @ 2cm, 1 @ 1.4cm July 30: Right Radical Orchiectomy Aug 2: Pathology report "100% Embryonal Carcinoma" Aug 20: Oncologist stages 2A, wants RPLND primary treatment Sept. 5: Urologist disagrees on RPLND primary, wants 2nd ct Sept 13: 2nd CT shows nodes now 2.4cm and 1.8cm Sept 15: Now Stage 2B, New treatment 3x BEP Oct. 2: Begin 3x BEP Nov. 28: Finish 3x BEP 2018 Jan. 04: first all clear CT

  • #2
    My case seemed very similar to yours. I’m not a doctor but I had the same issue right after nuelasta. Nuelasta I absolutely believe is the reason for the LDH rising. I’ve heard it from here and others that it can absolutely cause it to rise as mine did too have it.
    Last edited by dcalandrelli; 11-16-17, 10:12 AM.
    3/29/17 Diagnosed 100% Embryonal 4/10/17 Left I/O CT scan shows a few suspicious lymph (biggest 1.9 cm) 5/8/17 - 7/3/17 3xBEP 7/20/17 CT Scan Clear, AFP has uptick to 19 8/16/17 AFP Drops in half to 10, ALL CLEAR! 11/16/17 All Clear! AFP continues to drop!

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    • #3
      Technically, LDH is a measure of inflammation anywhere in the body, so not really a good tumor marker for TC, even though it is sometimes used as one.Combined with other tests, it may help to diagnose TC. On it's own, not conclusive in most cases.

      Dave
      Jan, 1975: Right I/O, followed by RPLND
      Dec, 2009: Left I/O, followed by 3xBEP

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