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What are the standard ranges for tumor markers? Conflicting info..

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  • What are the standard ranges for tumor markers? Conflicting info..

    I just did my 6 months (surveillance) post-I/O blood test (CT is on Monday). Although my 3 blood test results came back within the Standard range per my hospital (Stanford) I found different numbers on the web.
    What my hospital says: Std Range for AFP <10, for LDH <340 and for HCG < 1.4. The one that concerns me is LDH. Before I/O I was at 197, after I/O I was at 207, at 3 months I was at 196, and now at 6 months 226. Many sites have 190 as the normal max. Should I worry about this increase or is it within the margin of error of the test? (AFP = 2, HCG <0.6 but those have never moved, AFP in particular since I am pure seminoma).

  • #2
    Ldh is nothing more than cell death within the body. Many many things can cause it to go up or down. It is not a primary blood test but more a tool. If your execrise and are sore then more thsn likely your ldh csn go up. Dont look at it a a single test but look at it from a bigger picture with every thing combined.
    I am almost 5 yrs post hdc and my ldh is always up and above normal, but i am still cancer free. Does that make sense its just a tool ?
    Jan 2012- U/S mass in Left testicle
    Feb 2012- I/O performed to remove cancer
    Mar 1,2012- pathology pure seminoma
    Mar 7, 2012 PET SCAN stage IIa
    April 2012 Mayo clinic carbolite.
    May 2012 carbolite failed, started BEP x3
    August 7th 2012- BEP complete
    April 2013 CT/PET show relapse
    May 2013 RPLND
    Aug 2013 Relapse again Started VIeP x2
    Oct 2013 HDC AUTOLOGOUS
    Dec 2013 HDC completed CT/PETSCAN 1.1 cm x .8 cm right lower lung lobe
    Feb 2014 confirmed false positive all clear FINALLY !
    Jan 2015 1 year cancer free Pet/CT scan
    Jan 2016 2 years cancer free "Pet/CT scan
    Jan 2017 3 years cancer free "Pet/CT scan
    Jab 2018 4 years cancer free "Pet/CT scan, labs, xrays

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    • #3
      Originally posted by eodtech2001 View Post
      Ldh is nothing more than cell death within the body. Many many things can cause it to go up or down. It is not a primary blood test but more a tool. If your execrise and are sore then more thsn likely your ldh csn go up. Dont look at it a a single test but look at it from a bigger picture with every thing combined.
      I am almost 5 yrs post hdc and my ldh is always up and above normal, but i am still cancer free. Does that make sense its just a tool ?
      Thanks! It makes sense (and congrats on 4 years clear!)

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      • #4
        LDH isn't even really a tumor marker, it's a marker of inflammation in many areas of the body. Unless it was elevated when you still had active cancer, probably nothing to worry about. Also, the lab range is what is important, every lab will have a different "normal range". Internet #s are pretty much useless.
        Jan, 1975: Right I/O, followed by RPLND
        Dec, 2009: Left I/O, followed by 3xBEP

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