So I’m a EC/Seminoma relapse classified stage 3 due to high LDH (2,200) and distant node in the chest. I’m a little unusual with only two nodes total (other in abdomen) despite the distant site. Also I’ve always had zero AFP/HCG despite the EC component. I was 90% seminoma at pathology.
Anyways as Intermediate Risk I was given a plan of BEPx4. I’ve completed the EPx4 part and just have one more dose of Bleo left. I missed one dose earlier in cycle 3 due to being hospitalized, so my cumulative lifetime Bleo dose is currently 300 units (ten infusions).
Thus far I’ve avoided any known lung issues, but I’m a little worried about creeping closer to the maximum lifetime dose. I’ve read sources that suggest EPx4 is sufficient here. Wondering if I should talk to my Onc about skipping the last Bleo dose. I have an unrelated thoracic condition in addition to some mitral valve prolapse, thus my pre-chemo lung function while healthy was only 80% of normal. I was previously a physically active person in the outdoors pre-chemo and I really want to preserve my lung function best I can. Some of the European literature I’ve read suggests 300 units should be the max as opposed to 400 in the USA.
So many knowledgeable people here. Any thoughts? I’m leaning towards skipping the final Bleo but don’t want to make a dumb choice either. My Onc doesn’t treat a ton of TC and has been pretty much by the book throughout this.
Anyways as Intermediate Risk I was given a plan of BEPx4. I’ve completed the EPx4 part and just have one more dose of Bleo left. I missed one dose earlier in cycle 3 due to being hospitalized, so my cumulative lifetime Bleo dose is currently 300 units (ten infusions).
Thus far I’ve avoided any known lung issues, but I’m a little worried about creeping closer to the maximum lifetime dose. I’ve read sources that suggest EPx4 is sufficient here. Wondering if I should talk to my Onc about skipping the last Bleo dose. I have an unrelated thoracic condition in addition to some mitral valve prolapse, thus my pre-chemo lung function while healthy was only 80% of normal. I was previously a physically active person in the outdoors pre-chemo and I really want to preserve my lung function best I can. Some of the European literature I’ve read suggests 300 units should be the max as opposed to 400 in the USA.
So many knowledgeable people here. Any thoughts? I’m leaning towards skipping the final Bleo but don’t want to make a dumb choice either. My Onc doesn’t treat a ton of TC and has been pretty much by the book throughout this.
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