My husband was diagnosed with pure choriocarcinoma (negative testicular ultrasound) on 3/08 (after 4 weeks of complaining of sciatica type pain and multiple Dr visits and xrays, after 3wks they finally did blood work and it showed a possible infection, so off he goes to the ER he goes, during his workup multiple lung nodules were found, so he got admitted for cancer workup) he was started BEP x4 on 3/09. They found a large retroperitonium mass, multiple lung mets, 5 small brain mets, a few liver mets, and 1 spleen mass. Diagnosis was made by a biopsy on his retroperitonium mass. He has had 3 Cyberknife treatments for the brain mets. At diagnosis beta HCG was 330,630 After first 5day Chemo 759,672. At start of 3rd cycle (6wks) 1240. He also just had a PET/CT at mid treatment that has me very worried and concerned. It showed the tumor size on retroperitonium was the same, but with faint light. It still showed multiple lung mets with light. The liver and spleen mass have grow in size, but no light. He did not have PET prior to Chemo due to the urgency to get started. Also the cough he had at diagnosis is back since stopping the Decadron and has been on antibiotics without much improvement. He is having another pulmonary function test, but I read somewhere that might not be a good diagnostic tool for pulmonary toxicity. Very concerned about the results and since his tumor markers have consistently been dropping his oncologist was expecting better results as we were as well. He feels good only fatigued at times. He originally lost 35 lbs, but is now gaining some weight back.