Announcement

Announcement Module
Collapse
No announcement yet.

Bleomycin Doses 7 v 9

Page Title Module
Move Remove Collapse
X
Conversation Detail Module
Collapse
  • Filter
  • Time
  • Show
Clear All
new posts

  • deekz
    started a topic Bleomycin Doses 7 v 9

    Bleomycin Doses 7 v 9

    Hi All

    Just wondered if anyone had any knowledge regarding the following.

    i missed my first 2 single Bleo days due to issues with a blood condition I had. I’m now on my final long week and after the next two single Bleo days I will have had 7 doses. I spoke to oncology doc yesterday and they have said it’s my choice whether to add the missed Bleo doses on and have the full 9 doses. She informed me the research showed a big difference between 9 doses and 3 but was uncertain if missing 2 doses would have any impact.

    For now I have said as long as my body can take it to press on for the full 9 though I can’t say 4 Bleo days in a row is massively appealing 😂 I figure having had the Bleo and the associated life long effects would seem silly not to have the full 9.

    Again just wondered if you guys were aware of any knowledge regarding missing 2 doses. Also curious in case I’m unable to complete all 4.

    Thanks

    deekz

  • Davepet
    replied
    My understanding is that Bleo does not affect blood counts so no reason to omit it because they are low....

    Leave a comment:


  • darkdragon
    replied
    Hi deekz,

    I was omitted 2 Bleo shots, due to low counts (0 neutrophils, 0.2 lymphocytes, 0.1 monocytes).
    One was missed in the first cycle and the second in the second cycle. (details in signature about my case and treatment)

    Beside the problem with extremely low counts, on the 3rd BEP I started to have nosebleeds due to Neupogen shots. Had to take dexamethasone to stop the bleeding.
    I was not happy about that because I couldn't sleep.

    A Bleo side effect on me, which left my oncologist perplexed, was that in 3-4 hours after the Bleo administration, I had an urge to take a power nap.

    ​I read, after the treatment, stories here that Bleo should not be omitted, but maybe my oncologist didn't want to take additional risks.
    Almost a year and a half after the chemo, I'm safe and sound.

    Regards.

    Leave a comment:


  • Davepet
    replied
    I agree with Mike, can't recall adding missed Bleo at the end, normally missed doses are just missed doses. I've always assumed the bleo works to enhance the effects of the long week drugs, so adding it at the end is probably ineffective. Seek expert advise.

    Leave a comment:


  • Mike
    replied
    OK, having the bleomycin at weekly intervals sounds better, but unless my doctor has treated hundred and hundreds of patients and has extensive experience with testicular cancer, then I would ask them to ask a physician that has, to see what their opinions are as I just have not seen the adding on at the end process before. Mentioning BEPx3, I am guessing you are in the UK? If so, Dr. Tom Powles is a great doctor that yours could ask if they are not willing to reach out to the team at Indiana University. It is better to make the best decisions up front.

    Mike

    Leave a comment:


  • Davepet
    replied
    I don't recall any "bad tastes" but what sounded good to me definitely did change, chocolate was always good, and a few other foods that I rarely eat became favorites. lots of my normal staples just were unappealing.

    Leave a comment:


  • FBCoachC
    replied
    Originally posted by deekz View Post
    Hi guys

    Quick update, looks like going ahead with all 9 doses of Bleo. I tend to see a different onc doc each time I go and Wednesdays doc seemed to be in favour of just cracking on and finishing the doses. Seems quite common here to add missed Bleo doses at the end of the treatment. Did Wednesdays and feeling rough today but that's mainly due to my blood condition and anaemia rather than the Bleo. Had to have two bags of blood on the Bleo day which made for a long day. 3 more weeks till the finish line and boy I cant wait to get there.

    cant wait till I can look in the mirror and not be greeted by some ghoul like creature who looks like penguin from the batman movies lol. Or I guess I know now how Michael Jackson felt mwahaha.

    Here we get dexamethasone as the anti sickness during the long weeks and I like that steroid. On Bleo days its Hydrocortisone and I'm not as big a fan of that one I don't think lol. They must work for anti sickness cause I have not taken a single anti sickness med since starting chemo and as for appetite that has been insatiable. I have not been able to stop eating since starting lol although the horrible taste in my mouth is ruining things for me at the moment, but the best way to counter act that is to keep eating lol.

    Just to get through this last crash/nadir of the 5 day session and I am aiming for plain sailing next three weeks.

    peace and love to you all

    ​deekz
    Have no idea if this works for everyone, but the only way I found to cut through the bad taste was to eat extremely spicy food. The chipotle burrito bowl loaded with hot sauce the Saturday after my first long week may be the best thing ove ever eaten.

    Leave a comment:


  • deekz
    replied
    Hi guys

    Quick update, looks like going ahead with all 9 doses of Bleo. I tend to see a different onc doc each time I go and Wednesdays doc seemed to be in favour of just cracking on and finishing the doses. Seems quite common here to add missed Bleo doses at the end of the treatment. Did Wednesdays and feeling rough today but that's mainly due to my blood condition and anaemia rather than the Bleo. Had to have two bags of blood on the Bleo day which made for a long day. 3 more weeks till the finish line and boy I cant wait to get there.

    cant wait till I can look in the mirror and not be greeted by some ghoul like creature who looks like penguin from the batman movies lol. Or I guess I know now how Michael Jackson felt mwahaha.

    Here we get dexamethasone as the anti sickness during the long weeks and I like that steroid. On Bleo days its Hydrocortisone and I'm not as big a fan of that one I don't think lol. They must work for anti sickness cause I have not taken a single anti sickness med since starting chemo and as for appetite that has been insatiable. I have not been able to stop eating since starting lol although the horrible taste in my mouth is ruining things for me at the moment, but the best way to counter act that is to keep eating lol.

    Just to get through this last crash/nadir of the 5 day session and I am aiming for plain sailing next three weeks.

    peace and love to you all

    ​deekz

    Leave a comment:


  • JoeTheAstronaut
    replied
    Dave, those steroids will always be in memory as a ray of light!!

    Leave a comment:


  • Davepet
    replied
    I guess we are all different, I actually felt a boost in energy on my bleo only days (probably the anti nausea steroids, is my guess)
    Last edited by Davepet; 06-03-20, 03:37 PM.

    Leave a comment:


  • deekz
    replied
    Hi Mike

    i probably didn’t write that clear, by 4 in a row I meant spread over 4 weeks with a single day each week. It was my first two single days I missed after my first long cycle due to having to be admitted to hospital with complications from my blood condition.

    I was originally BEP over 3 days but as of cycle 2 they spread it over 5 days to try minimise the impact. I just finished my final 5 day stretch on Sunday which is 3 long cycles in total (feeling this one, so far I’ve had energy for days but feeling beat up now lol). Back in tomorrow for a single Bleo after a chat with onc docs in the morning.

    Your right Dave about the neuropathy I’m feeling that today already having finished the 5 day. Luckily and fingers crossed I have avoided fevers during all this so far. Not sure which drug is messing my mouth and teeth up but that sucks. Bleo is definitely a chest killer for a few days and causes tiredness but nothing major, I think the culmination of the 5 day kicks in around second Bleo which is i why I thought the second Bleo hit hard.

    thanks for the responses guys I’ll see what I find out tomorrow

    deekz

    Leave a comment:


  • Mike
    replied
    I've never really heard of adding makeup bleomycin doses to the end of a therapy and definitely not on a daily basis. I am assuming you had good risk disease if you were to receive BEPx3. Perhaps your doctor could reach out to a known expert, like the team at Indiana University, if they are not one and ask their opinion? Here is a list of experts from our friends at the TCRC. http://thetcrc.org/experts.html

    Mike

    Leave a comment:


  • Davepet
    replied
    I always found the Bleo only weeks pretty easy. Neuropathy is normally caused by the cisplatin, not the bleo. I've never heard of adding missed
    doses at the end, but I'm no doctor.

    Leave a comment:


  • deekz
    replied
    Hi Joe,

    yeah I believe hydrocortisone is given along with the Bleo. I’ve had 2 single doses so far, they were not too terrible though neuropathy and made a mess of my teeth and gums on the last one were the main issues. Kind of weird how the single Bleo doses seem to hit harder than when having it as part of the 5 day course, weird little drug lol.

    deekz

    Leave a comment:


  • JoeTheAstronaut
    replied
    Hey deekz, from memory if you can't do bleo, they might add on another round of EP - but it depends on your stage, size etc. If you were to play catch up, wouldn't they space it out, like 2 a week? Also, are you getting steroids with bleo? It made it sooo much easier for me!!

    Leave a comment:

Working...
X